Description

1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-4-Nitro-3-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its unique trifluoromethyl and nitro-substituted pyrrolopyridine core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in complex heterocycles.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-4-Nitro-3-(Trifluoromethyl)-
CAS No.	892414-50-5
Molecular Formula	C8H3ClF3N3O2
Molecular Weight	265.58 g/mol
Synonyms	6-Chloro-4-nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-4-nitro-3-(trifluoromethyl)-7-azaindole; 6-Chloro-4-nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-4-nitro-3-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-4-nitro-3-(trifluoromethyl)-; 892414-50-5; 6-Chloro-4-nitro-3-(trifluoromethyl)-7-azaindole
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine, 6-Chloro-4-Nitro-3-(Trifluoromethyl)- is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of cGMP and ICH guidelines for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurity profile, and other critical parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should be performed under subdued light or amber containers to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.