Description

3-Trifluoromethyl-1H-Pyrrolo[2,3-B]Pyridine CAS NO 892414-47-0 is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique pyrrolopyridine core functionalized with a trifluoromethyl group makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the development of chemical probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Trifluoromethyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	892414-47-0
Molecular Formula	C9H5F3N2
Molecular Weight	198.15 g/mol
Synonyms	3-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-(trifluoromethyl)-; 3-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 3-Trifluoromethyl-7-azaindole; 3-CF3-7-azaindole; 3-(Trifluoromethyl)-7-azaindole; 3-Trifluoromethyl-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Trifluoromethyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkali and fluorides; ensure it is stored separately from such materials. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.