Description

tert-Butyl2-Phenyl-3-Thioxo-1,4,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic triaza scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the development of new therapeutic agents.

Application

This specialized intermediate is designed for sophisticated synthetic applications, particularly in drug discovery and development.

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of novel drug candidates.
• Heterocyclic Compound Synthesis: Its unique spirocyclic structure makes it valuable for creating diverse and complex heterocyclic molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	tert-Butyl2-Phenyl-3-Thioxo-1,4,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate
CAS No.	892289-95-1
Molecular Formula	C18H23N3O2S
Molecular Weight	345.46 g/mol
Synonyms	tert-Butyl 2-phenyl-3-thioxo-1,4,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; 1,4,8-Triazaspiro[4.5]dec-1-ene-8-carboxylic acid, 2-phenyl-3-thioxo-, 1,1-dimethylethyl ester; 8-Boc-2-phenyl-3-thioxo-1,4,8-triazaspiro[4.5]dec-1-ene; Spirocyclic triaza derivative; BOC-protected spiro triazinethione.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets the high-purity requirements essential for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Production can be aligned with cGMP guidelines for advanced development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.