Description

3-(Benzyloxy)-5-Bromo-2-Chloropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the bromo and chloro substituents.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors for biochemical research.

Basic Information

Product Name	3-(Benzyloxy)-5-Bromo-2-Chloropyridine
CAS No.	891785-18-5
Molecular Formula	C12H9BrClNO
Molecular Weight	298.56 g/mol
Synonyms	5-Bromo-2-chloro-3-(phenylmethoxy)pyridine; 2-Chloro-5-bromo-3-benzyloxypyridine; 3-Benzyloxy-5-bromo-2-chloropyridine; Pyridine, 5-bromo-2-chloro-3-(phenylmethoxy)-; 891785-18-5; 5-Bromo-2-chloro-3-(benzyloxy)pyridine
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)-5-Bromo-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.