Description

3-Methyl-6-(4-Pyridinyl)Imidazo[2,1-B]Thiazole-5-Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) focused on developing new therapeutic agents, particularly in oncology and anti-infective drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The imidazothiazole-pyridine core structure is valuable for creating potential kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Employed in the development of chemical probes to study specific biological processes and protein functions.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up synthesis under cGMP conditions for clinical trial materials.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and bioorganic synthesis.

Basic Information

Product Name	3-Methyl-6-(4-Pyridinyl)Imidazo[2,1-B]Thiazole-5-Carboxaldehyde
CAS No.	891654-50-5
Molecular Formula	C12H9N3OS
Molecular Weight	243.28 g/mol
Synonyms	3-Methyl-6-(pyridin-4-yl)imidazo[2,1-b]thiazole-5-carbaldehyde; 3-Methyl-6-(4-pyridyl)imidazo[2,1-b]thiazole-5-carboxaldehyde; Imidazo[2,1-b]thiazole-5-carboxaldehyde, 3-methyl-6-(4-pyridinyl)-; 891654-50-5; 3-Methyl-6-(4-pyridinyl)imidazo[2,1-b]thiazole-5-carbaldehyde; 6-(4-Pyridinyl)-3-methylimidazo[2,1-b]thiazole-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Methyl-6-(4-Pyridinyl)Imidazo[2,1-B]Thiazole-5-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports development from research to commercial scale, adhering to relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.