Description

tert-Butyl 4-Bromo-2-Nitrobenzoate is a high-purity, synthetically valuable organic building block characterized by its bromo and nitro functional groups on a benzoate ester framework. This compound is essential for facilitating complex multi-step synthesis in advanced research and development, offering a protected carboxylic acid group and sites for selective functionalization. It is primarily sought after by pharmaceutical, agrochemical, and advanced material chemists for the construction of active pharmaceutical ingredients (APIs), specialty chemicals, and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted benzoic acid derivative.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where its bromo and nitro groups allow for further chemical modifications.
• Organic Ligand & Material Science: Serves as a starting material for creating complex organic ligands for catalysis or as a monomeric unit in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial R&D laboratories for method development, exploring new reaction pathways, and synthesizing complex molecular architectures.

Basic Information

Product Name	tert-Butyl 4-Bromo-2-Nitrobenzoate
CAS No.	890315-72-7
Molecular Formula	C11H12BrNO4
Molecular Weight	302.12 g/mol
Synonyms	4-Bromo-2-nitrobenzoic acid tert-butyl ester; Benzoic acid, 4-bromo-2-nitro-, 1,1-dimethylethyl ester; tert-Butyl 4-bromo-2-nitrobenzoate; 1,1-Dimethylethyl 4-bromo-2-nitrobenzoate; 2-Nitro-4-bromobenzoic acid tert-butyl ester; 890315-72-7; 4-Bromo-2-nitro-benzoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-Bromo-2-Nitrobenzoate is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency that meets the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to light or air should be avoided to maintain stability and purity. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.