Description

2-Amino-6-(Trifluoromethyl)Nicotinic Acid is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl-substituted pyridine core. This compound is essential for the synthesis of complex molecules, where its structure imparts desirable properties such as enhanced metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)Nicotinic Acid
CAS No.	890302-02-0
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	6-(Trifluoromethyl)-2-aminonicotinic acid; 2-Amino-6-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Carboxy-6-(trifluoromethyl)-2-aminopyridine; 2-Amino-3-carboxy-6-(trifluoromethyl)pyridine; 890302-02-0; 2-Amino-6-trifluoromethylnicotinic acid; 2-Amino-6-(trifluoromethyl)-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-(Trifluoromethyl)Nicotinic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.