Description

Ethyl 2-Amino-6-(Trifluoromethyl)Nicotinate is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the versatile amino and ester functionalities, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties such as metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for synthesizing functionalized ligands, complexing agents, and specialty polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical spaces in medicinal chemistry.
• Fluorine Chemistry Building Block: A valuable reagent for introducing fluorine-containing motifs into target molecules, a common strategy in modern drug design.

Basic Information

Product Name	Ethyl 2-Amino-6-(Trifluoromethyl)Nicotinate
CAS No.	890302-01-9
Molecular Formula	C9H9F3N2O2
Molecular Weight	234.18 g/mol
Synonyms	Ethyl 2-Amino-6-(trifluoromethyl)pyridine-3-carboxylate; 2-Amino-6-(trifluoromethyl)nicotinic acid ethyl ester; 3-Pyridinecarboxylic acid, 2-amino-6-(trifluoromethyl)-, ethyl ester; Ethyl α-amino-6-(trifluoromethyl)nicotinate; 890302-01-9; 2-Amino-6-trifluoromethyl-nicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and precise customer requirements. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all test results are available upon request, providing full traceability and assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.