Description

4-(4-Chloro-3-Pyridyl)-4-Oxobutyronitrile is a high-purity, versatile nitrile-containing pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a chloro-substituted pyridine ring and a reactive oxobutyronitrile moiety, makes it an invaluable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core.
• Ligand Synthesis: Serves as a starting material for creating novel chelating ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as non-linear optical (NLO) chromophores and charge-transport molecules.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(4-Chloro-3-Pyridyl)-4-Oxobutyronitrile
CAS No.	890100-84-2
Molecular Formula	C10H7ClN2O
Molecular Weight	206.63 g/mol
Synonyms	4-(4-Chloro-3-pyridinyl)-4-oxobutanenitrile; 4-Oxo-4-(4-chloro-3-pyridinyl)butyronitrile; 4-(4-Chloro-pyridin-3-yl)-4-oxo-butyronitrile; 4-(4-Chloro-3-pyridyl)-4-oxobutyronitrile; Butyronitrile, 4-(4-chloro-3-pyridinyl)-4-oxo-; 4-(4-Chloro-3-pyridinyl)-4-oxobutyronitrile; 3-Pyridinebutyronitrile, 4-chloro-γ-oxo-; γ-Oxo-4-(4-chloro-3-pyridinyl)butyronitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Chloro-3-Pyridyl)-4-Oxobutyronitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications tailored to meet the rigorous demands of process chemistry. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.