Description

5-(2-Chloro-3-Pyridyl)-5-Oxovaleronitrile is a versatile and high-value nitrile-containing pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture makes it a key building block for constructing complex heterocyclic systems, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-(2-Chloro-3-Pyridyl)-5-Oxovaleronitrile
CAS No.	890100-76-2
Molecular Formula	C10H9ClN2O
Molecular Weight	208.65 g/mol
Synonyms	5-(2-Chloro-3-pyridinyl)-5-oxopentanenitrile; 5-Oxo-5-(2-chloropyridin-3-yl)pentanenitrile; 4-(2-Chloro-3-pyridoyl)butyronitrile; 2-Chloro-3-(4-cyanobutyryl)pyridine; 5-(2-Chloro-3-pyridinyl)-4-oxopentanenitrile; 5-(2-Chloro-pyridin-3-yl)-5-oxo-valeronitrile; Valeronitrile, 5-(2-chloro-3-pyridinyl)-5-oxo-
EINECS	Contact for details

Quality Control

Our 5-(2-Chloro-3-Pyridyl)-5-Oxovaleronitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.