Description

Ethyl 4-(4-Chloro-3-Pyridyl)-4-Oxobutyrate is a high-purity organic intermediate featuring a pyridine core with a chloro substituent and an ester-linked oxobutyrate chain. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Building block for advanced herbicides, insecticides, and fungicides.
• Chemical Research & Development: Versatile precursor for heterocyclic chemistry and structure-activity relationship (SAR) studies.
• Material Science: Used in the synthesis of specialty polymers and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for scale-up and production of client-specific target molecules.

Basic Information

Product Name	Ethyl 4-(4-Chloro-3-Pyridyl)-4-Oxobutyrate
CAS No.	890100-63-7
Molecular Formula	C11H12ClNO3
Molecular Weight	241.67 g/mol
Synonyms	Ethyl 4-(4-chloropyridin-3-yl)-4-oxobutanoate; 4-(4-Chloro-3-pyridinyl)-4-oxobutanoic Acid Ethyl Ester; 3-Pyridinebutanoic acid, 4-chloro-γ-oxo-, ethyl ester; Butanoic acid, 4-(4-chloro-3-pyridinyl)-4-oxo-, ethyl ester; 890100-63-7; Ethyl 4-oxo-4-(4-chloro-3-pyridinyl)butyrate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Chloro-3-Pyridyl)-4-Oxobutyrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and specifications can be aligned with client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.