Description

2-Chloro-5-(3-Ethoxycarbonylbenzoyl)Pyridine is a high-purity, advanced pharmaceutical intermediate with the CAS number 890100-48-8. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure that enables targeted chemical transformations. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its pyridine core structure.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and process optimization studies.
• Material Science: Potential application in the synthesis of specialty polymers and ligands for catalysis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Chloro-5-(3-Ethoxycarbonylbenzoyl)Pyridine
CAS No.	890100-48-8
Molecular Formula	C15H12ClNO3
Molecular Weight	289.71 g/mol
Synonyms	2-Chloro-5-(3-ethoxycarbonylbenzoyl)pyridine; 3-(6-Chloropyridin-3-yl)-3-oxopropanoic acid ethyl ester; 3-(6-Chloro-3-pyridinyl)-3-oxopropanoic acid ethyl ester; Ethyl 3-(6-chloropyridine-3-carbonyl)benzoate; 890100-48-8; 2-Chloro-5-(3-carbethoxybenzoyl)pyridine; (3-Ethoxycarbonylphenyl)(6-chloropyridin-3-yl)methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(3-Ethoxycarbonylbenzoyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We are committed to meeting the stringent requirements of cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.