Description

5-Bromo-4-Methylnicotinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the efficient construction of complex heterocyclic scaffolds, which are pivotal for developing novel active compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce key functional groups and modulate molecular properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create labeled compounds or molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis services catering to specific client requirements for complex molecules.

Basic Information

Product Name	5-Bromo-4-Methylnicotinonitrile
CAS No.	890092-52-1
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	5-Bromo-4-methyl-3-cyanopyridine; 3-Cyano-5-bromo-4-methylpyridine; 4-Methyl-5-bromonicotinonitrile; Nicotinonitrile, 5-bromo-4-methyl-; 5-Bromo-4-methylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.