Description

1-(2-Hydroxymethyl-Phenyl)-Piperidine-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically versatile organic intermediate of significant importance in advanced pharmaceutical research and development. Its core value lies in its complex molecular architecture, which serves as a critical building block for constructing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, particularly for the synthesis of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and analgesic research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals for research and small-scale manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom manufacturers for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory organic synthesis.

Basic Information

Product Name	1-(2-Hydroxymethyl-Phenyl)-Piperidine-3-Carboxylic Acid Ethyl Ester
CAS No.	889956-07-4
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	Ethyl 1-[2-(hydroxymethyl)phenyl]-3-piperidinecarboxylate; 1-(2-Hydroxymethylphenyl)piperidine-3-carboxylic acid ethyl ester; 3-Piperidinecarboxylic acid, 1-[2-(hydroxymethyl)phenyl]-, ethyl ester; Ethyl 1-(2-(hydroxymethyl)phenyl)piperidine-3-carboxylate; CAS 889956-07-4
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxymethyl-Phenyl)-Piperidine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.