Description

1-(3-Hydroxymethyl-Phenyl)-Piperidine-4-Carboxylic Acid Ethyl Ester is a high-purity, versatile pharmaceutical intermediate and fine chemical building block. This compound is critical for the synthesis of complex molecules, offering a unique piperidine-carboxylate scaffold with a hydroxymethylphenyl substituent for further functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients. Its structural features make it a valuable precursor in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and analgesic research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its piperidine core.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for organic synthesis methodology development and novel compound libraries.

Basic Information

Item	Details
Product Name	1-(3-Hydroxymethyl-Phenyl)-Piperidine-4-Carboxylic Acid Ethyl Ester
CAS No.	889956-03-0
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	Ethyl 1-[3-(hydroxymethyl)phenyl]-4-piperidinecarboxylate; 1-(3-Hydroxymethylphenyl)piperidine-4-carboxylic acid ethyl ester; 4-Piperidinecarboxylic acid, 1-[3-(hydroxymethyl)phenyl]-, ethyl ester; UNII-8V7F4658QO; 889956-03-0; Ethyl 1-(3-(hydroxymethyl)phenyl)piperidine-4-carboxylate; 1-(3-Hydroxymethyl-phenyl)-piperidine-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1-(3-Hydroxymethyl-Phenyl)-Piperidine-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.