Description

3-(2,3-Dioxo-2,3-Dihydro-1H-Indol-5-Yl)-Benzoic Acid Methyl Ester is a high-purity, synthetic organic compound featuring a functionalized indole-2,3-dione (isatin) core, making it a valuable advanced pharmaceutical intermediate and key building block for medicinal chemistry research. Its molecular architecture is specifically designed for the synthesis of complex molecules targeting various biological pathways. This compound is primarily utilized by R&D laboratories and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

This specialized ester serves as a critical precursor in several advanced chemical synthesis pathways.

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates, particularly those with indole-derived structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new chemical entities for biological screening.
• Organic Synthesis: Key starting material or intermediate in multi-step synthetic routes for complex heterocyclic compounds.
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or affinity labels due to its reactive ester group and aromatic system.
• Agrochemical Research: Intermediate in the research and development of new active ingredients for crop protection.

Basic Information

Product Name	3-(2,3-Dioxo-2,3-Dihydro-1H-Indol-5-Yl)-Benzoic Acid Methyl Ester
CAS No.	889954-79-4
Molecular Formula	C16H11NO4
Molecular Weight	281.26 g/mol
Synonyms	Methyl 3-(2,3-dioxo-2,3-dihydro-1H-indol-5-yl)benzoate; 5-(3-Methoxycarbonylphenyl)isatin; Benzoic acid, 3-(2,3-dihydro-2,3-dioxo-1H-indol-5-yl)-, methyl ester; 3-(2,3-Dioxoindolin-5-yl)benzoic acid methyl ester; Methyl 3-(2,3-dioxoindolin-5-yl)benzoate
EINECS	Contact for details

Quality Control

Our production of 3-(2,3-Dioxo-2,3-Dihydro-1H-Indol-5-Yl)-Benzoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.