Description

2-(8-Amino-1,4-dioxaspiro[4.5]decan-8-yl)acetic acid is a specialized spirocyclic amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique fused ring structure and functional groups make it a valuable intermediate for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecule Design: Its amino acid backbone is integral for designing peptide analogs and other bioactive compounds with improved metabolic stability.
• Academic and Industrial R&D: Employed in chemical research for methodology development and exploring new chemical spaces in medicinal chemistry.
• Fine Chemical Production: Acts as a building block for the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	2-(8-Amino-1,4-dioxaspiro[4.5]decan-8-yl)acetic Acid
CAS No.	889949-15-9
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	8-Amino-1,4-dioxaspiro[4.5]decane-8-acetic Acid; 2-(8-Amino-1,4-dioxaspiro[4.5]decan-8-yl)ethanoic Acid; 8-Amino-8-carboxymethyl-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane-8-acetic acid, 8-amino-; (8-Amino-1,4-dioxaspiro[4.5]decan-8-yl)acetic Acid; Spirocyclic Amino Acid Derivative
EINECS	Contact for details

Quality Control

Our 2-(8-Amino-1,4-dioxaspiro[4.5]decan-8-yl)acetic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.