Description

Methyl 3-Amino-3-(2-Fluorophenyl)Propanoate is a high-purity fluorinated amino acid ester building block of significant importance in modern synthetic chemistry. Its core value lies in providing a versatile chiral scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of fluorinated drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance bioavailability and stability.
• Peptidomimetics & Bioactive Molecules: Serves as a constrained amino acid analog for designing peptide mimics and other biologically active compounds.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce chirality and the 2-fluorophenyl moiety into target molecules.
• Chemical Biology Probes: Useful for creating fluorinated probes and labels to study biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated intermediates.

Basic Information

Product Name	Methyl 3-Amino-3-(2-Fluorophenyl)Propanoate
CAS No.	889945-82-8
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	3-Amino-3-(2-fluorophenyl)propanoic acid methyl ester; Methyl 3-amino-3-(2-fluorophenyl)propionate; 2-Fluorobenzeneacetic acid, α-amino-, methyl ester; (3-Amino-3-(2-fluorophenyl)propyl) methyl ester; β-Amino-β-(2-fluorophenyl)propionic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-3-(2-Fluorophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.