Description

6-Chloro-2-Methylpyridine-3-Sulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. This compound is valued for its dual reactive sites, the chloro and sulfonyl chloride groups, which enable precise derivatization and the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, ligands for metal-organic frameworks (MOFs), and specialty chemicals.
• Chemical Derivatization: Employed in analytical chemistry and proteomics for labeling and modifying biomolecules due to its reactive sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) developing proprietary compounds.

Basic Information

Product Name	6-Chloro-2-Methylpyridine-3-Sulfonyl Chloride
CAS No.	889944-74-5
Molecular Formula	C7H7Cl2NO2S
Molecular Weight	240.11 g/mol
Synonyms	3-Chlorosulfonyl-6-chloro-2-methylpyridine; 2-Methyl-6-chloropyridine-3-sulfonyl chloride; 6-Chloro-2-picoline-3-sulfonyl chloride; 2-Methyl-6-chloro-3-pyridinesulfonyl chloride; 6-Chloro-2-methyl-3-pyridinesulfonyl chloride; 3-Pyridinesulfonyl chloride, 6-chloro-2-methyl-; 889944-74-5
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Methylpyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.