Description

2-Oxaspiro[3.3]heptane-6-carboxylic acid is a high-value, multifunctional spirocyclic building block of significant interest in advanced organic synthesis. Its unique bridged bicyclic structure containing both an ether and a carboxylic acid functional group makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the R&D of new herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts due to its rigid, three-dimensional structure.
• Material Science Monomer: Potential building block for specialty polymers with unique thermal and mechanical properties.
• Chemical Biology Probe: Utilized in the design of molecular probes and tools for studying biological systems and enzyme mechanisms.
• Academic & Contract Research: Essential for methodological development and exploration of new synthetic routes in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Oxaspiro[3.3]heptane-6-carboxylic Acid
CAS No.	889944-54-1
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	6-Carboxy-2-oxaspiro[3.3]heptane; 2-Oxaspiro[3.3]heptane-6-carboxylic acid; Oxaspiroheptanecarboxylic acid; Spiro[2.4]heptane-5-carboxylic acid, 1-oxa- (related); 1-Oxaspiro[2.4]heptane-5-carboxylic acid; 6-Oxaspiro[2.4]heptane-1-carboxylic acid (isomer); Bicyclo[3.1.1]heptane-6-carboxylic acid, 2-oxa-
EINECS	Contact for details

Quality Control

Every batch of 2-Oxaspiro[3.3]heptane-6-carboxylic acid is produced and analyzed under strict quality management protocols to ensure consistency and purity for critical R&D applications. Our standard material meets a typical purity specification of ≥97% (by HPLC), with comprehensive identity and impurity profiling performed. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, enantiomeric excess (if applicable), and residual solvent levels.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.