Description

4-Iodo-1-Methylpyridin-2(1H)-One is a high-purity, versatile heterocyclic building block used in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research, offering a reactive site for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific pyridone scaffolds.
• Material Science Research: Acts as a precursor for creating functionalized polymers or organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings.
• Ligand and Catalyst Development: Utilized to synthesize novel chelating ligands for metal complexes used in catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	4-Iodo-1-Methylpyridin-2(1H)-One
CAS No.	889865-47-8
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	4-Iodo-1-methyl-2(1H)-pyridinone; 4-Iodo-1-methylpyridin-2-one; 1-Methyl-4-iodopyridin-2(1H)-one; 4-Iodo-1-methyl-1,2-dihydropyridin-2-one; 4-Iodo-1-methyl-2-pyridone; 4-Iodo-N-methyl-2-pyridone; 889865-47-8
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Methylpyridin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.