Description

tert-Butyl 4-Bromo-2-Hydroxybenzoate is a versatile brominated phenolic ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromo substituent and a protected phenolic hydroxyl group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a halogenated salicylate core structure.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific bromo- and hydroxy-functionalized aromatic compounds.

Basic Information

Item	Details
Product Name	tert-Butyl 4-Bromo-2-Hydroxybenzoate
CAS No.	889858-09-7
Molecular Formula	C11H13BrO3
Molecular Weight	273.12 g/mol
Synonyms	4-Bromo-2-hydroxybenzoic acid tert-butyl ester; 2-Hydroxy-4-bromobenzoic acid tert-butyl ester; tert-Butyl 4-bromosalicylate; 4-Bromosalicylic acid tert-butyl ester; 889858-09-7; tert-Butyl 4-bromo-2-hydroxybenzoate; 4-Bromo-2-(tert-butoxycarbonyl)phenol
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Bromo-2-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.