Description

2-Chlorothiazol-5-Ylboronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel thiazole-containing drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate the chlorothiazole moiety.
• Material Science: Serves as a precursor for creating functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target validation.
• Process Chemistry: Enables scalable, efficient routes to complex molecules in pilot plant and manufacturing settings.
• Academic Research: A valuable reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Chlorothiazol-5-Ylboronic Acid Pinacol Ester
CAS No.	889672-72-4
Molecular Formula	C9H13BCINO2S
Molecular Weight	245.53 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-chlorothiazole; 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-Chlorothiazole-5-boronic acid pinacol ester; (2-Chlorothiazol-5-yl)boronic acid pinacol ester; 2-Chloro-5-(pinacolboryl)thiazole; 889672-72-4; 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 2-Chlorothiazol-5-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.