Description

1,2-Cyclopropanedicarboxylic Acid, 1,2-Diethyl Ester, (1R,2R)- is a high-value, stereochemically defined chiral building block. This compound is essential for the synthesis of complex molecules where precise three-dimensional structure is critical for biological activity or material properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides where the specific enantiomer can dictate efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical and Flavor/Fragrance Industry: Employed in the synthesis of complex, high-value specialty chemicals, including chiral components for flavors and fragrances.
• Academic and Industrial Research: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in medicinal chemistry.
• Material Science: Potential monomer or building block for creating polymers with specific chiral architectures for advanced material applications.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylic Acid, 1,2-Diethyl Ester, (1R,2R)-
CAS No.	889461-58-9
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(1R,2R)-1,2-Diethyl Cyclopropane-1,2-dicarboxylate; (1R,2R)-Diethyl Cyclopropane-1,2-dicarboxylate; (1R,2R)-Diethyl 1,2-Cyclopropanedicarboxylate; (1R,2R)-1,2-Cyclopropanedicarboxylic Acid Diethyl Ester; Diethyl (1R,2R)-1,2-Cyclopropanedicarboxylate; (1R,2R)-Rel-1,2-Cyclopropanedicarboxylic Acid Diethyl Ester; (R,R)-Diethyl Cyclopropane-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our (1R,2R)-1,2-Cyclopropanedicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and specific rotation are provided to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Provided on COA
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.