Description

(1S,2S)-Diethyl Cyclopropane-1,2-Dicarboxylate CAS NO 889461-57-8 is a high-purity, stereochemically defined chiral building block and synthetic intermediate. This compound is valued for its rigid cyclopropane ring and functional diester groups, which are crucial for constructing complex molecular architectures with precise three-dimensional control. It is primarily sought by R&D and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a constrained cyclopropane scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the cyclopropane moiety enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Employed in the development of specialty polymers and functional organic materials with tailored properties.
• Academic & Industrial R&D: A versatile tool for methodological development in organic synthesis and stereochemistry studies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	(1S,2S)-Diethyl Cyclopropane-1,2-Dicarboxylate
CAS No.	889461-57-8
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(1S,2S)-1,2-Cyclopropanedicarboxylic Acid Diethyl Ester; Diethyl (1S,2S)-1,2-Cyclopropanedicarboxylate; (1S,2S)-Diethyl Cyclopropane-1,2-Dicarboxylate; (-)-Diethyl (1S,2S)-1,2-Cyclopropanedicarboxylate; (1S,2S)-Cyclopropane-1,2-dicarboxylic Acid Diethyl Ester; Diethyl (1S,2S)-Cyclopropane-1,2-Dicarboxylate; (1S,2S)-Diethyl 1,2-Cyclopropanedicarboxylate
EINECS	Contact for details

Quality Control

Our (1S,2S)-Diethyl Cyclopropane-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.