Description

3-Bromo-1-Tosyl-1H-Pyrazolo[3,4-B]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is specifically engineered to serve as a critical precursor in the development of novel, complex molecular architectures. It is primarily sought after by research and development teams within the pharmaceutical, agrochemical, and material science industries for constructing active pharmaceutical ingredients (APIs), functional ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other biologically active small molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating organic electronic materials, such as charge-transport layers in OLEDs and OFETs.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Catalyst & Ligand Development: The pyrazolopyridine core can be functionalized to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs producing complex, patent-protected molecules for clients.

Basic Information

Product Name	3-Bromo-1-Tosyl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	889451-24-5
Molecular Formula	C15H12BrN3O2S
Molecular Weight	378.24 g/mol
Synonyms	3-Bromo-1-(4-methylphenyl)sulfonyl-1H-pyrazolo[3,4-b]pyridine; 3-Bromo-1-(p-toluenesulfonyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-bromo-1-[(4-methylphenyl)sulfonyl]-; 3-Bromo-1-tosyl-1H-pyrazolo[3,4-b]pyridine; 3-Bromo-1-(toluene-4-sulfonyl)-1H-pyrazolo[3,4-b]pyridine; 889451-24-5; Pyrazolo[3,4-b]pyridine, 3-bromo-1-(p-toluenesulfonyl)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-Tosyl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.