Description

5-Cyclopropyl-2-Methoxynicotinaldehyde is a versatile and high-value pyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both a cyclopropyl and an aldehyde functional group, makes it an essential building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging the bioactivity of the nicotinaldehyde core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its conjugated system.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	5-Cyclopropyl-2-Methoxynicotinaldehyde
CAS No.	888499-98-7
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	5-Cyclopropyl-2-methoxypyridine-3-carbaldehyde; 2-Methoxy-5-cyclopropylnicotinaldehyde; 3-Formyl-2-methoxy-5-cyclopropylpyridine; 5-Cyclopropyl-2-methoxy-3-pyridinecarboxaldehyde; 888499-98-7; 5-Cyclopropyl-2-methoxynicotinaldehyde; 2-Methoxy-5-cyclopropyl-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 5-Cyclopropyl-2-Methoxynicotinaldehyde adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.