Description

Methanone, [4-[2-[(6-Fluoro-3,4-Dihydro-2-Methyl-1(2H)-Quinolinyl)Carbonyl]-4-Morpholinyl]-1-Piperidinyl]-3-Isoquinolinyl- is a complex, high-purity organic compound featuring a fused quinoline and isoquinoline scaffold with morpholine and piperidine substituents. This compound is of significant interest as a key pharmaceutical intermediate or advanced research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, or other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: May be employed in vitro and in vivo studies to investigate specific biological pathways and protein interactions.
• Process Development: Used for scaling up synthetic routes and optimizing manufacturing processes for active pharmaceutical ingredients (APIs).
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, proprietary molecules for client-specific research projects.

Basic Information

Product Name	Methanone, [4-[2-[(6-Fluoro-3,4-Dihydro-2-Methyl-1(2H)-Quinolinyl)Carbonyl]-4-Morpholinyl]-1-Piperidinyl]-3-Isoquinolinyl-
CAS No.	888220-11-9
Molecular Formula	C30H33FN4O3
Molecular Weight	516.61 g/mol
Synonyms	6-Fluoro-2-methyl-1-{2-[4-(3-isoquinolinyl)-1-piperidinyl]-4-morpholinylcarbonyl}-1,2,3,4-tetrahydroquinoline; (6-Fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-[4-(3-isoquinolin-3-yl-piperidin-1-yl)-morpholin-2-yl]-methanone; 3-Isoquinolinyl-[4-[2-[(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)carbonyl]morpholin-4-yl]piperidin-1-yl]methanone; CAS 888220-11-9.
EINECS	Contact for details

Quality Control

Our Methanone, [4-[2-[(6-Fluoro-3,4-Dihydro-2-Methyl-1(2H)-Quinolinyl)Carbonyl]-4-Morpholinyl]-1-Piperidinyl]-3-Isoquinolinyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with client specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.