Description

Ethyl 3-Hydroxy-1-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Cyclopentane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its cyclopentane core and protected amino acid ester functionality. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics targeting metabolic and inflammatory pathways. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers requiring reliable, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel protease inhibitors and other small-molecule APIs.
• Peptidomimetic Research: Used in the development of peptide analogs and constrained scaffolds for drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for introducing the 1-amino-3-hydroxycyclopentane-1-carboxylate moiety into more complex molecular architectures.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced, high-efficacy crop protection agents.
• Academic & Industrial R&D: Employed in medicinal chemistry and process chemistry research for method development and scale-up studies.

Basic Information

Product Name	Ethyl 3-Hydroxy-1-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Cyclopentane-1-Carboxylate
CAS No.	887986-01-8
Molecular Formula	C13H23NO5
Molecular Weight	273.33 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)amino]-3-hydroxycyclopentane-1-carboxylic acid ethyl ester; Ethyl 1-[(tert-Butoxycarbonyl)amino]-3-hydroxycyclopentane-1-carboxylate; 1-Boc-amino-3-hydroxycyclopentane-1-carboxylic acid ethyl ester; 1-N-Boc-3-hydroxycyclopentane-1-carboxylic acid ethyl ester; (1R,3S)-Ethyl 1-((tert-butoxycarbonyl)amino)-3-hydroxycyclopentane-1-carboxylate (for chiral isomer); Boc-Cyclopentane-AA(OEt)-OH; 887986-01-8
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxy-1-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Cyclopentane-1-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and incompatible organic solvents. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.