Description

6-(3-Trifluoromethoxyphenyl)-Picolinic Acid is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced molecules due to its unique trifluoromethoxy-substituted aromatic system, which can impart desirable properties like metabolic stability and enhanced lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the R&D of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the picolinic acid core.
• Ligand in Catalysis: Serves as a precursor for creating specialized ligands in transition metal catalysis for complex organic transformations.
• Material Science Research: Investigated as a building block for advanced organic materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and target engagement.

Basic Information

Product Name	6-(3-Trifluoromethoxyphenyl)-Picolinic Acid
CAS No.	887983-58-6
Molecular Formula	C13H8F3NO3
Molecular Weight	283.20 g/mol
Synonyms	6-[3-(Trifluoromethoxy)phenyl]pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-[3-(trifluoromethoxy)phenyl]-; 6-(3-Trifluoromethoxyphenyl)-2-pyridinecarboxylic acid; 6-(3-(Trifluoromethoxy)phenyl)picolinic acid; 6-(α,α,α-Trifluoro-m-tolyloxy)picolinic acid; Picolinic acid, 6-(3-trifluoromethoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 6-(3-Trifluoromethoxyphenyl)-Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.