Description

6-(2,3-Difluorophenyl)Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its difluorophenyl and pyridine-carboxylic acid motifs. This compound matters as a critical intermediate in modern synthetic chemistry, enabling the precise construction of complex molecules with tailored properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the synthesis of kinase inhibitors and other biologically relevant scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Product Name	6-(2,3-Difluorophenyl)Pyridine-2-Carboxylic Acid
CAS No.	887983-10-0
Molecular Formula	C₁₂H₇F₂NO₂
Molecular Weight	235.19 g/mol
Synonyms	2,3-Difluoro-6-(2-pyridinyl)benzoic Acid; 6-(2,3-Difluorophenyl)picolinic Acid; 2-Pyridinecarboxylic acid, 6-(2,3-difluorophenyl)-; Picolinic acid, 6-(2,3-difluorophenyl)-; 887983-10-0; 6-(2,3-Difluorophenyl)-2-pyridinecarboxylic acid; 6-(2,3-Difluorophenyl)picolinate
EINECS	Contact for details

Quality Control

Our 6-(2,3-Difluorophenyl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard grade meets typical research and development requirements, with custom purity grades (e.g., >98%, >99%) available to support your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.