Description

6-(3-Fluorophenyl)-Picolinic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the fluorine atom and picolinic acid moiety can impart desirable biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine substituent for enhanced efficacy and environmental profile.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Chemical Biology: Utilized as a probe or tag in biochemical research due to its specific structural and electronic properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	6-(3-Fluorophenyl)-Picolinic Acid
CAS No.	887982-40-3
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-(3-Fluorophenyl)pyridine-6-carboxylic acid; 6-(3-Fluorophenyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-(3-fluorophenyl)-; 3-Fluoro-6-phenylpicolinic acid; Picolinic acid, 6-(3-fluorophenyl)-; 887982-40-3; 6-(3-Fluorophenyl)picolinate
EINECS	Contact for details

Quality Control

Our 6-(3-Fluorophenyl)-Picolinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.