Description

6-(2-Fluorophenyl)-Picolinic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a picolinic acid scaffold with a fluorinated aromatic ring, making it a versatile precursor for creating complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand Synthesis: Acts as a precursor for creating specialized chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and organic electronic materials due to its conjugated system and fluorine substitution.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	6-(2-Fluorophenyl)-Picolinic Acid
CAS No.	887982-35-6
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-(2-Fluorophenyl)pyridine-6-carboxylic acid; 6-(2-Fluorophenyl)pyridine-2-carboxylic acid; 2-Fluoro-2'-pyridine-6-carboxylic acid biphenyl; Picolinic acid, 6-(2-fluorophenyl)-; 887982-35-6; 6-(2-Fluorophenyl)picolinate
EINECS	Contact for details

Quality Control

Our 6-(2-Fluorophenyl)-Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.