Description

6-(Benzo[D][1,3]Dioxol-5-Yl)Nicotinic Acid is a high-purity, functionalized nicotinic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring a benzodioxole moiety, makes it a valuable intermediate for developing novel compounds with specific biological and material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create innovative active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, due to the benzodioxole pharmacophore.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for synthesizing organic electronic materials, dyes, and photoactive compounds.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	6-(Benzo[D][1,3]Dioxol-5-Yl)Nicotinic Acid
CAS No.	887976-73-0
Molecular Formula	C13H9NO4
Molecular Weight	243.22 g/mol
Synonyms	6-(1,3-Benzodioxol-5-yl)nicotinic acid; 6-(Benzo[d][1,3]dioxol-5-yl)pyridine-3-carboxylic acid; 5-(3-Carboxypyridin-6-yl)-1,3-benzodioxole; 6-(2H-1,3-Benzodioxol-5-yl)-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 6-(1,3-benzodioxol-5-yl)-; 6-(1,3-Benzodioxol-5-yl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-(Benzo[D][1,3]Dioxol-5-Yl)Nicotinic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.