Description

(6-[3-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in the unique physicochemical properties imparted by the trifluoromethyl group, which is essential for enhancing the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential kinase inhibitors and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Material Science: Serves as a precursor for advanced organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Chemical Synthesis: Acts as a versatile building block for constructing complex, fluorinated aromatic and heteroaromatic systems in medicinal and process chemistry.
• Ligand & Catalyst Development: Utilized in the design of novel chiral ligands or organocatalysts for asymmetric synthesis.
• Life Science Research: Employed as a biochemical tool or probe in academic and industrial research to study biological pathways and protein interactions.

Basic Information

Product Name	(6-[3-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol
CAS No.	887974-41-6
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	[3-(Trifluoromethyl)phenyl]-3-pyridinemethanol; (6-(3-(Trifluoromethyl)phenyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 6-[3-(trifluoromethyl)phenyl]-; 5-(Hydroxymethyl)-2-[3-(trifluoromethyl)phenyl]pyridine; 2-(3-(Trifluoromethyl)phenyl)-5-pyridinemethanol
EINECS	Contact for details

Quality Control

Our (6-[3-(Trifluoromethyl)Phenyl]Pyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting our clients' regulatory filing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.