Description

3-[5-(Hydroxymethyl)-2-Pyridyl]Benzonitrile is a versatile pyridine derivative and benzonitrile compound that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a hydroxymethyl and a nitrile group on aromatic rings, makes it a valuable intermediate for constructing complex molecular architectures. This high-purity intermediate is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides with specific pyridine-based activity.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and coordination chemistry applications.
• Material Science Research: Intermediate in the production of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Serves as a scaffold for developing fluorescent tags and molecular probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-[5-(Hydroxymethyl)-2-Pyridyl]Benzonitrile
CAS No.	887974-34-7
Molecular Formula	C13H10N2O
Molecular Weight	210.23 g/mol
Synonyms	3-(5-(Hydroxymethyl)pyridin-2-yl)benzonitrile; 2-(3-Cyanophenyl)-5-pyridinemethanol; 5-(Hydroxymethyl)-2-(3-cyanophenyl)pyridine; [5-(Hydroxymethyl)-2-pyridinyl]benzonitrile; Benzonitrile, 3-[5-(hydroxymethyl)-2-pyridinyl]-; 887974-34-7; 3-(5-Hydroxymethyl-pyridin-2-yl)-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-[5-(Hydroxymethyl)-2-Pyridyl]Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.