Description

[5-(2,3-Difluorophenyl)Pyridin-3-Yl]Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a difluorophenyl group and a hydroxymethyl substituent on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	[5-(2,3-Difluorophenyl)Pyridin-3-Yl]Methanol
CAS No.	887974-20-1
Molecular Formula	C12H9F2NO
Molecular Weight	221.20 g/mol
Synonyms	(5-(2,3-Difluorophenyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 5-(2,3-difluorophenyl)-; 5-(2,3-Difluorophenyl)-3-pyridinemethanol; 5-(2,3-Difluorophenyl)nicotinyl alcohol; 5-(2,3-Difluorophenyl)-3-hydroxymethylpyridine; 887974-20-1; (5-(2,3-Difluorophenyl)-3-pyridyl)methanol
EINECS	Contact for details

Quality Control

Every batch of [5-(2,3-Difluorophenyl)Pyridin-3-Yl]Methanol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.