Description

4-Isocyanato-1-Methyl-1H-Indole is a specialized aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its highly reactive isocyanate (-NCO) group, which enables the efficient construction of complex molecular architectures through reactions with amines, alcohols, and other nucleophiles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the indole scaffold imparts specific biological activity.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyurethanes, polyureas, and other high-performance polymers.
• Material Science: Employed in the creation of advanced functional materials, including coatings, adhesives, and resins with tailored properties.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new organic reactions and synthesizing complex heterocyclic compounds.

Basic Information

Product Name	4-Isocyanato-1-Methyl-1H-Indole
CAS No.	887922-92-1
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	1-Methyl-4-isocyanatoindole; 4-Isocyanato-1-methylindole; 1-Methyl-1H-indol-4-yl isocyanate; 4-Isocyanato-1-methyl-1H-indole; 1-Methylindole-4-isocyanate
EINECS	Contact for details

Quality Control

Our 4-Isocyanato-1-Methyl-1H-Indole is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.