Description

2-Pyrrolidin-1-Ylisonicotinic Acid, 1.5 Hydrate is a high-purity chemical intermediate featuring a unique pyridine-pyrrolidine hybrid structure. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise structural control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its heterocyclic framework.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical spaces and reaction pathways in medicinal chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.

Basic Information

Product Name	2-Pyrrolidin-1-Ylisonicotinic Acid, 1.5 Hydrate
CAS No.	887922-89-6
Molecular Formula	C10H12N2O2 · 1.5H2O
Molecular Weight	223.23 g/mol (Anhydrous Basis)
Synonyms	2-(1-Pyrrolidinyl)isonicotinic Acid Hemihydrate; 2-(Pyrrolidin-1-yl)isonicotinic Acid 1.5 Hydrate; 1.5-Hydrate of 2-(N-Pyrrolidino)isonicotinic Acid; 2-Pyrrolidin-1-ylpyridine-4-carboxylic Acid Hydrate; 4-Carboxy-2-pyrrolidin-1-ylpyridine Hydrate; PCIH; Isonicotinic acid, 2-(1-pyrrolidinyl)-, hydrate (1:1.5)
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrrolidin-1-Ylisonicotinic Acid, 1.5 Hydrate is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	10.0% - 12.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.