Description

Propanoic Acid, 2-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Oxy]-, 1,1-Dimethylethyl Ester, (2S)- is a high-purity, chiral chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors that require enantiomerically pure intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for drugs targeting specific biological pathways.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry is crucial for efficacy and environmental safety.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of complex flavors, fragrances, and advanced materials requiring precise stereochemical control.
• Peptidomimetics Research: Employed in medicinal chemistry for the development of peptide analogs and protease inhibitors, leveraging the phthalimide-protecting group and chiral center.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Can be utilized in the development of chiral catalysts or ligands for asymmetric transformations in organic chemistry.

Basic Information

Product Name	Propanoic Acid, 2-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Oxy]-, 1,1-Dimethylethyl Ester, (2S)-
CAS No.	887775-83-9
Molecular Formula	C15H17NO5
Molecular Weight	291.30 g/mol
Synonyms	(S)-tert-Butyl 2-((1,3-dioxoisoindolin-2-yl)oxy)propanoate; (2S)-2-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]propanoic acid tert-butyl ester; N-Phthaloyl-L-alanine tert-butyl ester; L-Alanine, N-phthaloyl-, tert-butyl ester; tert-Butyl N-phthaloyl-L-alaninate; (S)-2-(1,3-Dioxoisoindolin-2-yloxy)propionic acid tert-butyl ester; (S)-O-Phthalimido-lactic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Oxy]-, 1,1-Dimethylethyl Ester, (2S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.