Description

6-Methoxy-5-(Trifluoromethyl)-3-Pyridinemethanol is a high-value trifluoromethylated pyridine derivative, a crucial building block in modern synthetic chemistry. This compound matters for its role in introducing the metabolically stable trifluoromethyl group and a hydroxymethyl handle into complex molecular architectures, significantly influencing the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services (CDMO) producing complex, fluorinated molecules for clients.
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme function or biological pathways.

Basic Information

Product Name	6-Methoxy-5-(Trifluoromethyl)-3-Pyridinemethanol
CAS No.	887707-31-5
Molecular Formula	C8H8F3NO2
Molecular Weight	207.15 g/mol
Synonyms	5-(Trifluoromethyl)-6-methoxynicotinyl alcohol; (6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)methanol; 3-Pyridinemethanol, 6-methoxy-5-(trifluoromethyl)-; 6-Methoxy-5-trifluoromethyl-3-pyridylmethanol; 5-Trifluoromethyl-6-methoxy-3-pyridinemethanol; 6-Methoxy-5-(trifluoromethyl)pyridine-3-methanol
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-(Trifluoromethyl)-3-Pyridinemethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.