Description

5-Iodo-3-(Trifluoromethyl)-2(1H)-Pyridinone is a high-value, halogenated pyridinone derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and a trifluoromethyl group, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) and functional group transformations, leveraging the reactive iodine substituent.
• Ligand & Catalyst Development: Utilized in the design of novel ligands for transition metal catalysis and organocatalysts.
• Life Science Research: Employed as a biochemical probe or tool compound in academic and industrial research laboratories to study biological pathways.

Basic Information

Product Name	5-Iodo-3-(Trifluoromethyl)-2(1H)-Pyridinone
CAS No.	887707-23-5
Molecular Formula	C6H2F3INO
Molecular Weight	288.99 g/mol
Synonyms	5-Iodo-3-(trifluoromethyl)-1H-pyridin-2-one; 5-Iodo-3-(trifluoromethyl)pyridin-2(1H)-one; 2(1H)-Pyridinone, 5-iodo-3-(trifluoromethyl)-; 3-Trifluoromethyl-5-iodo-2-hydroxypyridine; 5-Iodo-3-trifluoromethyl-2-pyridone
EINECS	Contact for details

Quality Control

Our 5-Iodo-3-(Trifluoromethyl)-2(1H)-Pyridinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.