Description

1-(2-Nitro-Phenyl)-Azetidine-3-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex therapeutic areas. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecular entities with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic compounds and potential API candidates for neurological and oncological applications.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides, leveraging its nitro-phenyl and azetidine motifs.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the research of specialty polymers with unique optical or electronic properties.
• Academic & Contract Research: Essential reagent for methodology development and synthetic chemistry research in academic and CRO laboratories.

Basic Information

Product Name	1-(2-Nitro-Phenyl)-Azetidine-3-Carboxylic Acid Methyl Ester
CAS No.	887596-00-1
Molecular Formula	C11H12N2O4
Molecular Weight	236.23 g/mol
Synonyms	Methyl 1-(2-nitrophenyl)azetidine-3-carboxylate; 1-(2-Nitrophenyl)azetidine-3-carboxylic acid methyl ester; Azetidine-3-carboxylic acid, 1-(2-nitrophenyl)-, methyl ester; Methyl 1-(o-nitrophenyl)azetidine-3-carboxylate; 1-(o-Nitrophenyl)azetidine-3-carboxylic Acid Methyl Ester; 3-Carbomethoxy-1-(2-nitrophenyl)azetidine
EINECS	Contact for details

Quality Control

Our 1-(2-Nitro-Phenyl)-Azetidine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.