Description

3-(2-Bromo-Pyridin-3-Yl)-3-Oxo-Propionitrile is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromo-substituent and a reactive cyano-ketone moiety, makes it an invaluable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Building block for creating functionalized ligands and organic electronic materials.
• Chemical Synthesis: Versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions.
• Heterocyclic Chemistry: Core scaffold for constructing fused pyridine and other nitrogen-containing heterocycles of biological interest.

Basic Information

Product Name	3-(2-Bromo-Pyridin-3-Yl)-3-Oxo-Propionitrile
CAS No.	887593-99-9
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	2-Bromo-3-(2-cyanoacetyl)pyridine; 3-Oxo-3-(2-bromopyridin-3-yl)propanenitrile; 2-Bromo-3-pyridyl cyanomethyl ketone; 3-(2-Bromo-3-pyridinyl)-3-oxopropanenitrile; Propanenitrile, 3-(2-bromo-3-pyridinyl)-3-oxo-; (2-Bromopyridin-3-yl)(cyanomethyl) ketone
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Bromo-Pyridin-3-Yl)-3-Oxo-Propionitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.