Description

4-(Bromo-Methoxycarbonyl-Methyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, multi-functional piperidine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a bromo and a tert-butyloxycarbonyl (Boc) protected amine, makes it an essential intermediate for constructing complex pharmacophores and fine chemicals. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) and metabolic disorder treatments.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the piperidine moiety for enhanced biological activity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, enzyme inhibitors, and tagged compounds used in drug discovery and biochemical research.
• Peptidomimetics & Macrocycle Synthesis: The reactive bromomethyl and protected amine groups facilitate its incorporation into peptide analogs and constrained macrocyclic compounds.
• Material Science Research: Potential precursor for specialty polymers, ligands for catalysis, and advanced organic materials requiring specific piperidine functionalities.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds for clients.

Basic Information

Product Name	4-(Bromo-Methoxycarbonyl-Methyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887593-26-2
Molecular Formula	C13H22BrNO4
Molecular Weight	336.22 g/mol
Synonyms	1-Boc-4-(bromomethylcarbonylmethyl)piperidine; tert-Butyl 4-[(bromoacetyl)methyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(bromoacetyl)methyl]piperidine; 4-(Bromoacetylmethyl)-1-N-Boc-piperidine; 4-(2-Bromo-1-oxoethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-N-Boc-4-(bromoacetylmethyl)piperidine; Piperidine-1-carboxylic acid, 4-[(bromoacetyl)methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(Bromo-Methoxycarbonyl-Methyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released based on comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and ensure product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.