Description

2-Bromomethyl-5-nitropyridine is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and an electron-withdrawing nitro substituent, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with pyridine-based cores.
• Ligand and Catalyst Development: Used to create sophisticated chelating ligands for metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the development of organic electronic materials, such as electron-transport layers and photoactive compounds.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Bromomethyl-5-nitropyridine
CAS No.	887588-20-7
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	5-Nitro-2-(bromomethyl)pyridine; 2-(Bromomethyl)-5-nitropyridine; Pyridine, 2-(bromomethyl)-5-nitro-; (5-Nitropyridin-2-yl)methyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromomethyl-5-nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices for chemicals.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.