Description

3-(3-Methoxypropylamino)Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate and building block of significant commercial importance. This compound is valued for its role as a key synthon in the development of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug candidates, especially those containing pyrrolidine and aminoalkyl ether motifs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing molecular libraries in drug discovery programs targeting various disease pathways.
• API Synthesis: Used in the production route for Active Pharmaceutical Ingredients (APIs), where the tert-butyloxycarbonyl (Boc) protecting group and methoxypropylamino side chain are essential functional elements.
• Fine Chemical Manufacturing: Employed in the custom synthesis of specialty chemicals for agrochemical, material science, and catalyst development applications.
• Process Chemistry Development: Acts as a standardized starting material for optimizing scalable and robust synthetic routes in pilot plants and commercial production.

Basic Information

Product Name	3-(3-Methoxypropylamino)Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887587-38-4
Molecular Formula	C13H26N2O3
Molecular Weight	258.36 g/mol
Synonyms	1-Boc-3-(3-methoxypropylamino)pyrrolidine; tert-Butyl 3-[(3-methoxypropyl)amino]pyrrolidine-1-carboxylate; 3-[(3-Methoxypropyl)amino]-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 3-[(3-methoxypropyl)amino]-1-pyrrolidinecarboxylate; 3-(3-Methoxypropylamino)pyrrolidine-1-carboxylic acid tert-butyl ester; N-Boc-3-(3-methoxypropylamino)pyrrolidine; Pyrrolidine, 3-[(3-methoxypropyl)amino]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 3-(3-Methoxypropylamino)Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical R&D and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as confirmed by HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.