Description

1-[2-[(tert-Butyldiphenylsilyl)Oxy]Ethyl]Piperazine is a high-value, protected piperazine derivative used as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Peptidomimetic Chemistry: Used to introduce the piperazine moiety into peptide-like structures to modulate bioavailability and receptor binding.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Can be utilized to functionalize polymers, imparting specific chemical properties for advanced material science applications.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents and herbicides.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	1-[2-[(tert-Butyldiphenylsilyl)Oxy]Ethyl]Piperazine
CAS No.	887583-71-3
Molecular Formula	C22H32N2OSi
Molecular Weight	368.59 g/mol
Synonyms	1-(2-((tert-Butyldiphenylsilyl)oxy)ethyl)piperazine; 2-(1-Piperazinyl)ethanol, 1-(1,1-dimethylethyl)-1,1-diphenylsilyl ether; N-(2-((tert-Butyldiphenylsilyl)oxy)ethyl)piperazine; TBDPS-protected hydroxyethylpiperazine; tert-Butyl(2-(piperazin-1-yl)ethoxy)diphenylsilane; 1-[2-(tert-Butyldiphenylsiloxy)ethyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-[2-[(tert-Butyldiphenylsilyl)Oxy]Ethyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.