Description

6-(Trifluoromethyl)Pyridine-2-Carbonitrile is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and nitrile functional groups make it a high-value intermediate for creating complex molecules with enhanced properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing advanced organic electronic materials, such as charge-transport molecules or liquid crystals.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying the influence of fluorine atoms on molecular properties.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up development.

Basic Information

Product Name	6-(Trifluoromethyl)Pyridine-2-Carbonitrile
CAS No.	887583-52-0
Molecular Formula	C7H3F3N2
Molecular Weight	172.11 g/mol
Synonyms	2-Cyano-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)picolinonitrile; 2-Pyridinecarbonitrile, 6-(trifluoromethyl)-; 6-Trifluoromethyl-2-cyanopyridine; α,α,α-Trifluoro-2-cyano-6-picoline; Picolinonitrile, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a strict quality management system to ensure batch-to-batch consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.