Description

1-Boc-4-[(2-Fluoro-Phenylamino)-Methyl]-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine scaffold. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries to develop new active ingredients and optimize synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile, protected amine functionality.
• API (Active Pharmaceutical Ingredient) Development: Incorporated into the synthetic pathway of potential APIs requiring a fluorinated aniline-piperidine moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and clinical trial materials.
• Agrochemical Research: Employed in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Used as a scaffold for creating molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	1-Boc-4-[(2-Fluoro-Phenylamino)-Methyl]-Piperidine
CAS No.	887582-20-9
Molecular Formula	C18H27FN2O2
Molecular Weight	322.42 g/mol
Synonyms	1-Boc-4-[(2-Fluoroanilino)methyl]piperidine; tert-Butyl 4-{[(2-fluorophenyl)amino]methyl}piperidine-1-carboxylate; N-(2-Fluorophenyl)-1-(tert-butoxycarbonyl)piperidine-4-methanamine; 1-BOC-4-[(2-FLUORO-PHENYLAMINO)-METHYL]-PIPERIDINE; 4-[(2-Fluorophenylamino)methyl]piperidine-1-carboxylic acid tert-butyl ester; Piperidine, 4-[[(2-fluorophenyl)amino]methyl]-, 1-(1,1-dimethylethyl) ester; Boc-4-(2-fluoroanilinomethyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-[(2-Fluoro-Phenylamino)-Methyl]-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.